Men with Autoimmune or ANY Chronic Illness

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Wednesday, November 11, 2009

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What is APS ?
Antiphospholipid Syndrome (APS) is a rare immunological disorder characterized by recurring blood clots. Blood clots can form in any blood vessel of the body.
The specific symptoms and severity of APS vary greatly from case to case, depending upon the exact location of a blood clot and the organ system affected. APS may occur as an isolated disorder (primary antiphospholipid syndrome), or may occur along with another autoimmune disorder such as Systemic Lupus Erythematosus (SLE) as secondary antiphospholipid syndrome.

APS is characterized by the presence of antiphospholipid antibodies in the body. Antibodies are specialized proteins produced by the body's immune system to fight infections. In individuals with APS, cetain antibodies mistakenly attach to healthy tissue. This healthy tissue contain certain proteins that bind to phospholipids. Phospholipids are a type of fat molecule that is involved in the proper function of cell membranes found throughout the body. The reason for these antiphospholipid antibodies attacking the phospholipid proteins, and the process by which they cause blood clots are not known. Fatigue is a reported effect of this over-active immune response. As you can see, it is a complicated disease with very simple outcomes. It wreaks havoc to our bodies, our families, and our lives. It can be a big burden to carry while trying to live our best life possible.

An even more rare manifestation of the disease is Catastrohpic APS (CAPS), which causes mutli-organ failure. It has a high morbidity rate of nearly 50 percent of those afflicted. Women with APS suffer repeated mis-carriages with pregnancy, among other various complications.

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